Benign esophageal tumors are not common, and most of them are leiomyomas; schwannomas are rarely seen. Symptoms worsen as the tumor increases in size. A preoperative diagnosis is difficult, and the definitive diagnosis is often established by histological features and immunohistochemical stain after surgery. An 82-year-old woman had dysphagia for 2 years and exertional dyspnea for 1 year. She had a huge esophageal submucosal tumor with nearly total obstruction of the middle esophagus and compression of the left main bronchus. Tumor enucleation followed with primary suture of the mucosal defect through a right mini-thoracotomy under video-assistance was performed successfully. To our knowledge, this is the first report of an elderly woman with a huge schwannoma located in the middle esophagus that was successfully treated with surgical enucleation instead of total or subtotal esophagectomy.