Atrial Fibrillation and Central Sleep Apnea in Patients with Ischemic Stroke

Ping-Chi Liu ； Chung-Yao Chen ； Chung-Chieh Yu

《胸腔醫學》 35卷1期 (2020/03) Pp. 1-9

摘要

Introduction: Atrial fibrillation (AF) and central sleep apnea (CSA) are both common in patients with ischemic stroke and have been associated with adverse outcomes. However, whether AF is associated with CSA in patients with stroke has not been well studied. The primary objective of this study was to investigate the association between AF and CSA in patients with ischemic stroke. Methods: This retrospective study consecutively included patients with ischemic stroke that were admitted for neurorehabilitation, had clinically suspected sleep-disordered breathing, and that had undergone in-hospital overnight polysomnography. The basic clinical data, underlying diseases and test results of the CSA and non-CSA patients were compared and analyzed. Results: Of the 116 patients with sleep-disordered breathing, 26 (22.4%) were found to have CSA. Patients in the CSA group had a higher prevalence of AF than those in the non- CSA group (42.3% versus 11.1%). AF was positively associated with the presence of CSA (OR, 7.381; 95% CI, 1.39-27.25; P = 0.003), after adjusting for common confounders. Conclusion: The co-aggregation of AF and CSA suggests important clinical implications for simultaneous screening and management of both conditions in patients with ischemic stroke.

關鍵字

atrial fibrillation ； central sleep apnea ； ischemic stroke