Nontuberculous mycobacteria (NTM) can be isolated from a variety of environmental sources. These free-living organisms have potential to cause a variety of infections, such as lung disease, soft tissue infection, and disseminated disease. Treatment for NTM can include anti-mycobacterial therapy and surgical management. Here, we present a case of dyspnea after recent median sternotomy, with disseminated NTM infection.