透過您的圖書館登入
IP:18.191.88.249
  • 期刊

Influenza Pneumonia Associated with Invasive Pulmonary Aspergillosis Requiring Venovenous Extracorporeal Membrane Oxygenation Support: A Case Report and Literature Review

摘要


Invasive pulmonary aspergillosis (IPA) is an often underdiagnosed, lethal coinfection in critically ill patients who have influenza pneumonia. Here, we reported the case of a 49-year-old man without classic immunocompromised host factors for IPA. The patient was diagnosed with influenza and IPA coinfection complicated by acute respiratory distress syndrome. He recovered successfully after antifungal agent treatment and venovenous extracorporeal membrane oxygenation (ECMO) support. With regard to the effect of ECMO on the pharmacokinetics of voriconazole, therapeutic drug monitoring was performed to ensure an optimal antifungal agent dose. This case report highlights the importance of early diagnosis and treatment of IPA, and the role of therapeutic drug monitoring in patients receiving ECMO.

延伸閱讀