Conservation Therapy of Breast Cancer

乳癌保守治療法

楊友華(Andrew Y. H. Young) ； 葉啟源(Chi-Yuan Yeh) ； 賴允亮(Yeun-Liang Lai) ； 張國華(Kou-Hwa Chang) ； 鍾昌宏(Chang-Hung Chung) ； 賴易成(Yi-Cherng Lai)

《放射治療與腫瘤學》 2卷1期 (1995/03) Pp. 35-39

https://doi.org/10.6316/TRO/199502(1)35

摘要

從1987至1994年，21位早期乳癌病人（第一期和第二期）在本院接受保守腫瘤切除手術，並保存了完好的乳房外型，亦稱乳房保守治療，手術後再到放射腫瘤科接受局部放射治療。鈷－六十治療機(Theratron Cobalt-60 unit)或6-MV光子直線加速器(6-MV Linear Accelerator unit)作為治療工具，並用切面照野(Tangential Field)照射患側乳房至5040 cGy分為28次照射，另外在開刀疤痕處再用180 cGy分次量之電子射線(6-MeV or 9-MeV Electron beam)，局部照射1000 cGy至2000 cGy。除去兩位失去追蹤之病患，十九位病患之數據分析結果得出，五年存活率為80%，以及百分之百的局部控制率，成效實在令人鼓舞。總而言之，乳房保守治療輔加放射線局部照射之方法，用於早期乳癌病患是值得鼓勵的，因為它除了可以得到良好之局部控制外，還保存了病患乳房之完整美觀，可謂完美之至。

關鍵字

乳房保守治療法 ； 放射治療 ； 乳癌

並列摘要

From 1987 to 1994, twenty-one cases of early breast cancer (stage I or II) received conservative operation to preserve breasts. They were referred to the Department of the Radiation Oncology for radiotherapy. Tangential field irradiation using a Theratron Cobalt-60 unit or a 6-MV Linear Accelerator unit was given to the involved breast with a dose of 5040 cGy in 28 fractions, followed by surgical sear boost of 1000 to 2000 cGy in 180 cGy per fraction with 6-MeV or 9-MeV electron beam. With two patients lost to follow-up after radiotherapy excluded, nineteen patients were analysed with an encouraging results showing an 80% 5-year overall survival rate and a 100% local control rate.
In conclusion, Breast Conservation Therapy (BCT) with adjuvant irradiation should be encouraged for early stage breast cancer because it has the benefits of a good local tumor control and superior breast cosmetic result.

並列關鍵字

Breast conservation therapy ； Radiotherapy ； Breast Cancer