Outpatient Continuous Infusional Chemotherapy with Ambulatory Infusional Puma-The Early Experience of Outpatient Chemotherapy Unit at the Veterans General Hospital-Taipei

門診病人使用可攜帶式灌注幫浦進行連續性灌注化學治療－台北榮民總醫院門診化學治療室之早期經驗

陳盛鈺(S. Y. Chen) ； 梁麗麗(L. L. Liang) ； 張小玲(S. L. Chang) ； 孟孟蓮(M. L. Meng) ； 顏上惠(S. H. Yen) ； 羅志剛(C. K. Low) ； 季匡華(K. H. Chi) ； 陳光耀(K. Y. Chen)

《放射治療與腫瘤學》 5卷1期 (1998/03) Pp. 19-25

https://doi.org/10.6316/TRO/199805(1)19

摘要

目的：評估門診病人使用中央靜脈導管與可攜帶式灌注幫浦進行連續性灌注化學治療的併發症。
材料與方法：本研究自1990年9月至1991年6月共收集了90例病人，中央靜脈導管裝置包括Port-A導管，或是Hickman導管。使用灌注幫浦為Walkmed 430型系列，根據病歷及護理記錄作回溯性分析。
結果：總共治療666人次中，27人次(4.1%)有併發症之記錄。有1人次因Hickman導管引起敗血症而住院將導管拔除，有5人次因導管和藥袋聯結脫落，5人次因幫浦操作不當而故障， 4 人次因導管阻塞而需使用urokinase沖灌，4人次因電池耗盡而故障，4人次因Hickman導管脫出而需重裝，3人次藥袋破裂而藥物滲出，有l人次不明原因回血導致故障。其他沒有主要的不良併發症。
結論：門診病人使用中央靜脈導管與可攜帶式灌注幫浦，進行連續性灌注化學治療是一種安全的、方便的及低併發症的治療模式。

關鍵字

化學治療 ； 連續性灌注化學治療 ； Hickman's導管 ； Port-A導管

並列摘要

Purpose: We plan to evaluate the patterns of complication, and conveniences of outpatient ambulatory continuous infusional chemotherapy delivery system through implantable semipermanent central vein catheter and portable infusional pump in the treatment of cancer patients at the outpatient chemotherapy unit of VGH-Taipei.
Materials and Methods: From September 1990 to June 1991, we collected ninety cancer patients who received chemotherapy through either Hickman's catheter or Port-A Cath and Walkmed 430 iv infusion pump for outpatient infusional chemotherapy. Patients' chart and nursing records were analyzed retrospectively.
Results: In a total of 666 treatment courses, there were 27 (4.1%) complications recorded. One patient developed catheter related sepsis who needed hospitalization and catheter removal thereafter. There were 5 courses (5 patients) with bag and tube disconnection, 5 courses (5 patients) with pump malfunction from improper operation, 4 courses (4 patients) of catheter obstruction which need urokinase salvage, 4 courses (4 patients) of pump failure from battery exhaustion, 4 courses ( 4 patients) of Hickman's catheter dislodged, 3 courses ( 3 patients) of drug leakage from reservoir, 1 course (1 patient) of machine malfunction from unknown reason. No other major morbidity were noted.
Conclusion: Outpatient continuous infusional chemotherapy with implantable central vein catheter and portable infusional pump is a safe, convenient with low complication treatment modality.

並列關鍵字

Chemotherapy ； Continuous infusional chemotherapy ； Hickman's catheter ； Port-A catheter