Treatment Results of Polymorphic Reticulosis at Veterans General Hospital-Taipei

台北榮民總醫院多形性網細胞增多症之治療成果

夏錫生(Hsi-Sheng Chsia) ； 梁棉榮(Mien-Jung Liang) ； 曾玉華(Yuk-Wah Tsang) ； 許志宏(Chih-Hung Shu) ； 李永賢(Wing-Yin Lee) ； 季匡華(Kwan-Hwa Chi) ； 陳光耀(Kuang-Yao Chen) ； 趙靜宜(Jing-Yi Chao) ； 顏上惠(Sang-Hue Yen)

《放射治療與腫瘤學》 6卷1期 (1999/03) Pp. 25-32

https://doi.org/10.6316/TRO/199906(1)25

摘要

Purpose: Retrospectively review the treatment results of polymorphic reticulosis (now called angiocentric T-cell lymphoma) patients at Veterans General Hospital-Taipei over the past fifteen years (1982-1997).
Materials and Methods: From December 1982 to December 1997, there were 40 patients diagnosed of polymorphic reticulosis at Veterans General Hospital-Taipei. There were 35 male patients and 5 female patients. The age of the patients ranged from 14 to 78 years old. The follow-up period ranged from 1 to 172 months. Medical histories, laboratory and X-ray examinations and modalities of treatment from medical records of each patient were reviewed. Five patients received chemotherapy alone, 19 patients received radiotherapy alone and 16 patients received radiotherapy combined with chemotherapy or surgery.
Results: The 5-year disease-free survival rate of all patients was 35%. The 5-year disease-free survival rate for patients receiving radiotherapy alone was 57%. It was 19% for patients treated with radiotherapy plus surgery, chemotherapy or both; and 8% only for patients received surgery combined with other treatments. Number of involved sites (=1), Karnofsky scale (＞70), non-surgery treatment are positive statistical prognostic factors. There were 23 patients died and 9 of them have evidence of disease progression (5 cases of distant metastasis and 4 cases of locoregional recurrence). There were 2 patients relapsed in 15 patients who received chemotherapy, and there were 7 patients relapsed in 25 patients who without chemotherapy.
Conclusion: Polymorphic reticulosis had excellent local control rate by radiotherapy. Chemotherapy may be benefit for prevention of distant metastasis and local recurrence. Number of involved site(s), good Karnofsky scale, and non-surgical treatment are associated better prognosis.

關鍵字

多形性網細胞增多症 ； 放射治療 ； 惡性淋巴腫瘤

並列摘要

Purpose: Retrospectively review the treatment results of polymorphic reticulosis (now called angiocentric T-cell lymphoma) patients at Veterans General Hospital-Taipei over the past fifteen years (1982-1997).
Materials and Methods: From December 1982 to December 1997, there were 40 patients diagnosed of polymorphic reticulosis at Veterans General Hospital-Taipei. There were 35 male patients and 5 female patients. The age of the patients ranged from 14 to 78 years old. The follow-up period ranged from 1 to 172 months. Medical histories, laboratory and X-ray examinations and modalities of treatment from medical records of each patient were reviewed. Five patients received chemotherapy alone, 19 patients received radiotherapy alone and 16 patients received radiotherapy combined with chemotherapy or surgery.
Results: The 5-year disease-free survival rate of all patients was 35%. The 5-year disease-free survival rate for patients receiving radiotherapy alone was 57%. It was 19% for patients treated with radiotherapy plus surgery, chemotherapy or both; and 8% only for patients received surgery combined with other treatments. Number of involved sites (=1), Karnofsky scale (＞70), non-surgery treatment are positive statistical prognostic factors. There were 23 patients died and 9 of them have evidence of disease progression (5 cases of distant metastasis and 4 cases of locoregional recurrence). There were 2 patients relapsed in 15 patients who received chemotherapy, and there were 7 patients relapsed in 25 patients who without chemotherapy.
Conclusion: Polymorphic reticulosis had excellent local control rate by radiotherapy. Chemotherapy may be benefit for prevention of distant metastasis and local recurrence. Number of involved site(s), good Karnofsky scale, and non-surgical treatment are associated better prognosis.

並列關鍵字

Polymorphic reticulosis ； Radiotherapy ； Malignant lymphoma.