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強度調控放射治療腔內膠片劑量品質保證

Oral Cavity Dosimetry for Intensity Modulated Radiation Therapy Quality Assurance

摘要


目的:在使用新的強度調控放射治療技術治療腫瘤時,藉由放射膠片來做強度調控放射治療品質保證,是非常重要的一項工作。本研究目的為對GafChromic EBT膠片進行一系列的特性測量及校正,並建立計讀的方式與程序,最後將膠片放置於口腔癌及舌癌病患口腔裡,度量其所接受之輻射劑量。 材料及方法:在研究的過程裡,先對GafChromic EBT膠片進行一系列的特性測量與校正並建立計讀程序,之後將膠片放置於固態水假體之參考點與直接放置在病人口腔內,來針對強度調控放射治療模式下測量其劑量,將其所得之劑量與治療計畫互相比較,經由使用這一種口腔輻射劑量度量方法,來驗證臨床上實際得到的照射劑量。結果:在本研究中,假體進行強度調控放射治療模式照射,皆以靜態式step-and-shoot的方式照射以及以兩種不同之幾何照野照射來模擬病人,其一照野的測量結果比治療計畫多2%,其二照野的測量結果比治療計畫少37%。而在口腔輻射測量結果中,口腔癌病患測量結果與治療計畫相比,其平均誤差為256%(+0.5%~+53%),而舌癌病患測量結果與治療計畫相比,其平均誤差為-526%(-34%~-71%)。 結論:經由本實驗瞭解GafChromic EBT膠片之結構與特性,以及建立一套包括校正與計讀程序,且建議在使用時所應該注意的事項,以降低誤差的發生。並藉由直接的方式,將膠片置放於病患口腔內計讀其劑量,以達到品質保證的目的。

並列摘要


Purpose: The intensity modulated radiation therapy (IMRT) quality assurance (QA) by film is a very important job when using the new technique of IMRT to treat tumor. The aim of this study is first to measure the characteristic of the GafChromic EBT film, calibration and establish a procedure of reading, then we do an oral cavity dosimetry for buccal and tongue cancers. Materials and Methods: We use the new developed GafChromic EBT film for oral cavity dosimetry study in this work. First, we measure the characteristic of the film and establish a procedure for reading. Second, we put the film into the solid water phantom's reference point and the patient's oral cavity to do oral cavity dosimetry for IMRT. We have compared the results with treatment planning system. Our oral cavity dosimetry can verify the real tumor dose in clinic situation. Results: The measured dosimetry results for solid water phantom are 2% more than treatment planning system in case one, and 3.7% less than treatment planning system in case two. For oral cavity dosimetry, the error is 2.56% for buccal cancer and 5.26% for tongue cancer Conclusion: By this study, we can understand the structure and characteristic of this newly developed film as well as establish procedure of calibration and readings. In order to reduce error and increase accuracy, we also made suggestions for using this film to do dose measurements. Through patient oral cavity dosimetry, we can achieve the goal of quality assurance.

被引用紀錄


邱君洋(2011)。呼吸位移補償系統之設計與驗證〔碩士論文,國立臺北科技大學〕。華藝線上圖書館。https://doi.org/10.6841/NTUT.2011.00713
吳宜珊(2011)。利用輻射變色軟片評量肺部腫瘤接受強度調控放射治療技術時的劑量評估〔碩士論文,中臺科技大學〕。華藝線上圖書館。https://doi.org/10.6822/CTUST.2011.00031
陳麗萍(2009)。乳癌強度調控放射治療之表面劑量測量〔碩士論文,中臺科技大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0099-0508201017254012
陳麗萍(2009)。乳癌強度調控放射治療之表面劑量測量〔碩士論文,中臺科技大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0099-0508201017254352

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