Radiotherapy for Large Liver Hemangioma: Report on Four Cases and Review of Literature

肝血管瘤之放射治療結果：病例報告與文獻回顧

柯建佑(Chien-Yu Ker) ； 汪昶佑(Chang-Yu Wang) ； 梁雲(Stephen Wan Leung)

《放射治療與腫瘤學》 22卷3期 (2015/09) Pp. 231-238

https://doi.org/10.6316/TRO/201522(3)231

摘要

前言：血管瘤是最常見的良性肝腫瘤且大多數是無症狀的。對於伴隨著症狀的血管瘤，手術切除是常見的治療方式。然而對於無法手術切除的肝血管瘤，放射線治療相對於經動脈栓塞術卻為不常見的治療選擇。我們在此報告四位病例採用放射線治療肝血管瘤並作文獻回顧。病例報告：本文採用回溯性分析，四位病例報告皆為女性，年齡為50至61歲。所有病人都有右上腹疼痛以及腹脹的症狀。一位病人為手術後數年後復發肝血管瘤。其餘三位為經導管肝動脈栓塞術後症狀無明顯改善。照射劑量為50到59.4格雷分別照射20到33次，共4到7週。在最新的追蹤中，所有的病人皆無症狀，且肝血管瘤體積縮小比例從80.8%到98.0%，無任何相關副作用。結論：放射線治療可用於伴隨著症狀的肝臟血管瘤，且治療結果良好。

關鍵字

肝臟血管瘤 ； 放射線治療

並列摘要

Background: Hemangioma is the most common benign liver tumor, and mostly asymptomatic. For symptomatic hemangioma, surgical resection is the most common treatment. In unresectable hemangiomas, one of the alternative managements is radiotherapy, a relatively uncommon choice compared to transcatheter arterial embolization. We present our experience of four cases of liver hemangioma treated with fractionated radiotherapy and reviewed the literatures. Case Presentation: A total of four female patients, aged between 50 to 61 years, were retrospectively analyzed. They presented with symptoms of right upper quadrant pain and abdominal fullness. One patient had recurrent liver hemangioma years after liver resection. The other three received transcatheter arterial embolization to hemangioma with limited improvement in symptoms. All patients received radiotherapy with a total dose of 50-59.4 Gy in 20-33 fractions over a 4-7 week period. At the latest follow-up, the regression rate for these liver hemangiomas was 80.8% to 98.0% without radiation-associated adverse effects and the patients remained symptom-free. Conclusions: Radiotherapy is a feasible treatment for symptomatic liver hemangioma with good outcome.

並列關鍵字

Hepatic hemangioma ； Radiotherapy