Palliative Radiotherapy for the Extensive Skin Metastasis of Breast Cancer: A Case Report and Review of the Literature

乳癌倂廣泛皮膚轉移之姑息放射性治療：案例報告與文獻回顧

王南宗(Nan-Tsung Wang) ； 蕭世禎(Su-Zun Shaw) ； 雷德(Louis Tak Lui) ； 李星怡(Hsing-Yi Lee) ； 吳錦榕(Ching-Jung Wu)

《放射治療與腫瘤學》 22卷3期 (2015/09) Pp. 239-247

https://doi.org/10.6316/TRO/201522(3)239

摘要

乳癌是台灣婦女死亡率第四位之癌症，且較易擴散至骨骼、肝臟、肺臟以及腦部。然而，皮膚之轉移卻代表著較不良的預後。本文將報告一42歲女性乳癌病患於結束輔助性放射治療後17個月隨即反覆發生皮膚轉移的案例。此案例在化學治療控制失敗後接受了螺旋刀作為姑息性放射治療，但治療成果只獲得了部分的反應且有相當的副作用。姑息性放射治療也許可以作為乳癌病患病皮膚轉移的治療選擇之一，但對於患者實質助益與傷害間仍應仔細權衡。本文針對案例的治療過程加以詳述，並且回顧相關文獻。

關鍵字

乳癌 ； 皮膚轉移 ； 放射治療 ； 姑息性

並列摘要

We report a 42-year-old Taiwanese woman with recurrent skin metastasis who presented with extensive forebreast, and abdominal skin metastasis approximately 17 months after initial adjuvant radiotherapy. The patient was treated with Helical Tomo-Therapy at a total dose of 50 Gy given in 2 Gy per fraction per day. Skin metastases in this case showed only partial response to radiotherapy, and new metastatic lesions developed during the treatment. Radiotherapy might be considered as a palliative treatment option for the skin metastasis of breast cancer. The treatment course of this case is described and previous reports are reviewed in this article.

並列關鍵字

Breast cancer ； Skin metastasis ； Radiotherapy ； Palliation