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摘要


C-反應蛋白(C-reactive protein,簡稱CRP)可以預測心臟血管疾病發生率的危險性,且比低密度脂蛋白-膽固醇(LDL-C)是心血管疾病更好的的預測指標。大多數橫斷面研究顯示,身體活動量或體適能水準與C-反應蛋白有明顯相關;大多數縱斷面研究也顯示,有氧運動訓練可以明顯降低C-反應蛋白。顯示運動具有抗發炎效果,而達到降低心血管疾病的罹患率。Gielen等(2005)指出,運動明顯降低C-反應蛋白濃度,有四種可能的機轉:(1)藉由降低中心肥胖(腰臀比)而減少脂肪組織分泌IL-6和TNF-α;(2)改善內皮細胞功能失調而減少內皮細胞釋放IL-1和IL-6;(3)降低因單核球活化而增加細胞激素的產生;(4)減少其他組織(例如骨骼肌)產生細胞激素。

參考文獻


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