腦中風併發的肌少症之診斷與治療：文獻回顧

Diagnosis and Treatment of Stroke-related Sarcopenia: A Narrative Review

陳思翰(Szu-Han Chen) ； 傅鐵城(Tieh-Cheng Fu)

《台灣復健醫學雜誌》 50卷2期 (2022/12) Pp. 95-102

https://doi.org/10.6315/TJPMR.202212_50(2).0002

摘要

腦中風會造成患者肢體的功能缺損，同時伴以活動量減少，營養攝取不夠以及慢性發炎狀態，因而有偏高的肌少症發生率。肌少症會進一步影響中風病患的肢體功能與生活品質，所以肌少症對中風病患是一個重要的健康議題。目前文獻對於腦中風患者病發的肌少症之診斷與治療的研究仍然相當有限。本文擬以現有的文獻證據來對腦中風後之肌少症之診斷與治療做一個討論。

關鍵字

腦中風（stroke） ； 肌少症（sarcopenia） ； 診斷（diagnosis） ； 治療（intervention）

並列摘要

Stroke patients have a high prevalence of sarcopenia due to the presence of several risk factors, including immobilization, impaired feeding, sympathetic activation, inflammation, and denervation. The occurrence of sarcopenia further exacerbates the disability caused by the stroke. Thus, appropriate diagnosis and intervention for sarcopenia is an important health issue for the stroke population. The article discusses the dilemma in diagnostic tests and potential treatment for stroke-related sarcopenia based on the currently available literature evidence.

並列關鍵字

stroke ； sarcopenia ； diagnosis ； intervention

參考文獻

Ajmo CT, Jr., Collier LA, Leonardo CC, et al. Blockade of adrenoreceptors inhibits the splenic response to stroke. Exp Neurol 2009;218:47-55.

Arnal MA, Mosoni L, Boirie Y, et al. Protein pulse feeding improves protein retention in elderly women. Am J Clin Nutr 1999;69:1202-8.

Baumgartner RN, Waters DL, Gallagher D, et al. Predictors of skeletal muscle mass in elderly men and women. Mech Ageing Dev 1999;107:123-36.

Blackman MR, Sorkin JD, Münzer T, et al. Growth hormone and sex steroid administration in healthy aged women and men: a randomized controlled trial. Jama 2002;288:2282-92.

Bobos P, Nazari G, Lu Z, et al. Measurement Properties of the Hand Grip Strength Assessment: A Systematic Review With Meta-analysis. Arch Phys Med Rehabil 2020;101:553-65.