In this study, the use of electrostatic spraying mixing deoxyribonucleic acid (DNA) and sodium alginate into DNA / calcium alginate micro-particles. DNA can be used in adsorption of benzene compounds and adsorb polluted water. To improve the water-soluble DNA, using the alginate modified DNA to non-water-soluble state. Particulate sample can be increase the surface area of the adsorption of the dye and calculate adsorption rate. The results showed that different types of dyes structure and DNA / Calcium alginate micro-particles adsorption rate is not the same. The results show that DNA/ calcium alginate micro-particles has maximum adsorption ratio 82.2% for acid dye.