In the traditional Chinese culture, happiness is a state of harmony, which means that human beings have a positive emotion from individuals to a group. From the cradle to the grave, the sole meaning of life of mankind is to pursue happiness, which enhances life satisfaction and the value of existence. Recently, despite the fact that a great number of literatures investigating the meaning of happiness in terms of ethics, politics, and economics, no study comprehensively discussed and elucidated the concept of happiness through an evidence-based and systemic approach. We utilized the concept analysis model proposed by Walker and Avant (2011), which was a method for investigating causes and effects of happiness. It has already been investigated for years and implemented mainly through gathering associated articles, and comparing the characteristics of typical, unique, and opposite cases regarding happiness. Overall, our review help propose an educational program for nursing staff to understand the importance of happiness and its future application.