After aortic dissection, the acute physical and psychological discomfort poses a significant challenge for medical care, emphasizing the critical role of attentive and comprehensive care. From October 29 to November 4, 2020, Roy's adaptation model was employed for nursing assessment, identifying acute pain, respiratory function failure, and delirium as the primary health problems. Intensive care units, being confined spaces, present unique challenges as family members are unable to accompany patients due to various instruments and pipelines. This isolation can lead to heightened susceptibility to strangers and increased psychological pressure. To address these issues, relaxation techniques were implemented to alleviate pain, and the Triflow-II was taught to enhance respiratory function. Meeting times were flexibly adjusted, and family members were encouraged to accompany patients. The use of the intensive care unit confusion assessment for delirium, cross-team meetings to refine treatment approaches, and involving patients and their families in cardiac rehabilitation were instrumental in managing delirium. Additionally, individualized care measures, such as adjusting the sleep cycle, were undertaken to address specific patient needs. These interventions not only reduced anxiety but also contributed to a quicker recovery.