新生兒紅斑性狼瘡是一種由母親的自體抗體藉由胎盤傳給胎兒的免疫性疾病。它是一種可以影響到胎兒全身許多器官及系統的疾病。典型新生兒紅斑性狼瘡的皮膚病灶是在陽光曝曬處出現分散的、環型、紅色脫屑斑塊。而皮膚血管擴張在新生兒紅斑性狼瘡中也是一種主要的皮膚表徵。我們回溯性研究分析並追蹤過去十年來在台大醫院的13例新生兒紅斑性狼瘡,結果發現有五例新生兒紅斑性狼瘡在身上特定處有明顯及持續性的血管擴張表徵。
Neonatal lupus erythematosus (NLE), an immune-mediated disease with multisystem involvement in infants, is associated with the transplacental transfer of maternal autoantibodies. Discrete, annular, scaly, erythematous patches and plaques at photo-exposed areas are typical cutaneous lesions of neonatal lupus erythematosus. Cutaneous telangiectasia is also a key feature in neonatal lupus erythematosus. We retrospectively analyzed and followed 13 cases of NLE in National Taiwan University Hospital in the past 10 years. There is a total of five children who were noted to have prominent and persistent telangiectases at specific sites in the course of NLE.