嗜伊紅球性脂層炎是一種罕見的脂層炎,特徵是侵犯皮下脂肪的發炎細胞以嗜伊紅球為主。可能伴隨異位性體質、過敏、蚊蟲咬傷、鏈球菌感染、頷口蟲病、自體免疫性疫病和惡性腫瘤等疾病。我們報告一位22歲男性病人,主訴於下巴反覆出現又癢又痛的紅色腫塊達2年之久。皮膚病理切片呈現在皮下脂肪小葉間有許多嗜伊紅球的侵犯,並且延伸到脂肪中隔之間。實驗室檢查發現血中嗜伊紅球增多及IgE&特異性IgE的數值昇高。因此,吾人診斷此病例為嗜伊紅球性脂層炎合併異位性體質,並對文獻稍作回顧。
Eosinophilic panniculitis, characterized by a prominent infiltration of subcutaneous fat with eosinohils , is a rare panniculitis. Atopy, allergy, arthropod assault, Streptococcus infection, gnathostomaiasis, autoimmune disease, and malignancy may be the associated disorders. We herein present a 22-year-old male with recurrent, itchy and tender erythematous swelling of his chin for 2 years. The histopathology of lesional skin biopsy revealed infiltration of numerous eosinophils in the subcutaneous fat lobules with focal septal extension. Laboratory examinations showed blood eosniophilia and elevated total and specific IgE level. A diagnosis of eosinophilic panniculitis with atopic background was made and the literature was reviewed.