- 期刊
Keratitis, Ichthyosis and Deafness Syndrome-A Case Report and Literature Review
角膜炎－魚鱗癬－耳聾症候群－病例報告及文獻回顧
摘要
“KID症狀群＂是由Skinner等人於1981年所提出的縮寫，用來表示此症候群中常見的角膜炎－魚鱗癬－耳聾之表現。這是一個極少見的症候群，約70個病例曾經被報導過。本文報告一個28歲男性，出現皮膚過度角化、雙側聽力喪失、失明、禿髮及小腦萎縮的案例。除了典型的臨床表現之外，此病人於6歲開始出現行走困難的現象，現在則處於臥床的狀態。我們同時發現病人於下肢出現紅色疣狀突起的巨大斑塊，臨床上懷疑是鱗狀細胞癌，而切片結果為角質增厚及棘層變厚。這些疣狀突起的斑塊在給予潤膚劑、角質溶解劑及局部塗抹抗生素後獲得改善。我們同時回顧與此症候群有關的文獻。
關鍵字
無資料並列摘要
The acronym ”KID syndrome” was proposed by Skinner et al. in 1981 to represent keratitis, ichthyosis and deafness. It is a rare syndrome and about 70 cases have been reported. Herein, we report a 28-year-old male with keratoderma, bilateral deafness, total blindness, alopecia and cerebellar hypoplasia. Our patient started to have walking difficulties at the age of 6 and is now bed-ridden. Several huge erythematous plaques with verrucous surface were noted over the lower limbs. Squamous cell carcinoma was suspected clinically and skin pathology revealed only hyperkeratosis and acanthosis. The verrucous plaques improved after treatment with emollient, keratolytics and topical antibiotics. We also reviewed the literature concerning this rare syndrome.