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Fenofibrate-Induced Photosensitivity-A Case Report and Literature Review

Fenofibrate引起之光敏感反應-病例報告暨文獻回顧

摘要


Fenofibrate是世界上最常用的降血脂藥物之一,其引起皮膚副作用的機率約為2%,而光敏感反應則被認為是一個少見的表現,我們在此提出一例經由光貼膚測試確認為fenofibrate引起光敏感反應之本土病例。回顧文獻,自1980年代起至今,fenofibrate引起光敏感反應的報告並不多見。我們同時也探討fenofibrate及ketoprofen的交叉光敏感反應。

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並列摘要


Fenofibrate, a fibric acid derivative, is among the most commonly used antihyperlipidemic medications. Although variable kinds of cutaneous eruption occurred in about 2% of fenofibrate users, photosensitivity was assumed to be a rare manifestation. Herein we report a case of fenofibrate-induced photosensitization confirmed by photopatch testing. Reviewing the literature, fenofibrate-induced photosensitivity has been infrequently reported since 1980s. Besides, we also discuss the cross-photosensitization between fenofibrate and ketoprofen.

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