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幾丁聚醣:新的牙周組織工程材料

Chitosan: A New Candidate for Periodontal tissue Engineering

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摘要


隨著生醫材料的研究與發展,幾丁質這個在天然有機物當中含量僅次於纖維素的多醣体其重要性就更加受人矚目。幾丁質係無脊椎動物外骨略的重要組成,而幾丁聚醣則是幾丁質去乙醯化後所得之產物,兩者皆具有良好的生物相容性及生物可降解性,臨床上不僅具有抗菌、止血、促進傷口癒合等特性,更是一個沒有毒性療效又好的牙周再生材料。本文將就幾丁質及幾丁聚醣的構造、如何製備及各種不同的研究結果,來證實其在臨床運用對牙周組織修復的之可行性。

並列摘要


Chitin is second only to cellulose as the most abundant natural biopolymer. It is an important structural component of the exoskeleton of invertebrates and is a very stable polysaccharide. Chitosan is a derivative of chitin made by treating is with hot strong alkali which results in abundant deacetylation of side chains. Chitin and chitosan have various biological effects such as biocompatibility, biodegradability, non-toxicity, activation of host defense to prevent infection, acceleration of wound healing and so on. It is potentially a new regenerative materials that will be discussed in this paper.

並列關鍵字

chitin chitosan hemostasis antimicrobial wound healing bone formation

被引用紀錄


余虹德(2006)。幾丁聚醣/磷酸三鈣複合薄膜的製備與性質〔碩士論文,淡江大學〕。華藝線上圖書館。https://doi.org/10.6846/TKU.2006.00789
沈泰宇(2010)。葡萄糖胺對拔牙後齒槽修復之影響:動物實驗評估〔碩士論文,國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2010.02057
車立雯(2005)。靈芝子實體纖維之幾丁質及幾丁聚醣之製備〔碩士論文,臺北醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0007-1704200714542184
詹進忠(2006)。可注射式聚乳酸/幾丁聚醣/非晶型磷酸鈣牙周再生阻隔材之活體評估〔碩士論文,臺北醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0007-1704200715050223

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