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富含血小板血漿在骨再生方面之應用

The Use of Platelet-rich Plasma in Bone Regeneration

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摘要


在牙科目前促進骨再生的技術中,最常使用的是可吸收及不可吸收的再生膜,來引導組織再生,而近年來,學者為了促進術後傷口止血及癒合,開始使用富含血小板血漿(platelet-rich plasma, PRP)這種材料,它是藉由抽取病人自身血液,經分層離心方法分離出高濃度的血小板,可幫助術後止血,又因含有數種生長因子,被認為有助於骨再生,通常會合併移植骨使用。本文藉文獻回顧探討何謂PRP、其製備過程、並提出目前應用在骨再生的情形。

並列摘要


Guided tissue regeneration (GTR) with non-absorbable membrane or absorbable membrane is a well-established treatment modality for periodontal disease. Platelet-rich plasma (PRP) is recently used to facilitate wound healing and hemostasis. The α granule of platelet contains coagulation factors. In addition, some growth factors released from α granule and PRP are considered as bone regeneration material. This article discusses the nature and characteristics of PRP, the processing of the materials, as well as the outcomes of using PRP for bone regeneration in various clinical situations.

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