Anthropologists play an important role in medical education and clinical practice in the United States. They do this by assisting medical students and medical doctors to solve problems associated with patient illness. This article introduces the background of medical anthropology. Following the introduction, there is a discussion of four major concepts of clinically applied anthropology. These are: cultural factors, the explanatory model, disease versus illness, and the semantic network. The aim of this paper is to attract medical doctors and scholars to conduct research on clinical anthropology in Taiwan.