Methadone Maintenance Treatment in a General Hospital

美沙冬替代療法臨床執行經驗與成效分析－以某綜合醫院為例

劉筱雯(Hsiao-Wen Liu) ； 許建中(Chien-Chung Hsu) ； 林怜利(Lain-Li Lin) ； 武維馨(Wei-Hsin Wu)

《台灣精神醫學》 23卷3期 (2009/09) Pp. 215-222

https://doi.org/10.29478/TJP.200909.0006

摘要

目的：本研究目的在探討美沙冬替代療法的執行情況，並比較治療組與退出組間之差異。方法：本研究為回溯性研究，共收集379位美沙冬替代療法個案之人口學及臨床資料，以描述性統計、T考驗與卡方考驗分析。結果：隨治療時間增加尿液嗎啡篩檢陽性比例下降；女性較易維持治療；藥物劑量、尿液陽性比例、出席率在兩組達顯著差異，而年齡、婚姻狀況與是否感染愛滋並無顯著差異。結論：當發現早期退出治療的個案，應該給予相關協助，並建議未來應對此進行介入性研究以使個案能持續治療。

關鍵字

美沙冬替代療法 ； 海洛因使用者 ； 海洛因依賴

並列摘要

Objectives: Previous studies have revealed the efficacy of methadone maintenance treatment (MMT). In this study, we intended to investigate clinical efficacy of the MMT and to compare the differences between dropout and remaining heroin users in the MMT. Methods: We conducted a retrospective chart review. We recruited 379 participants, and collected information of their social demography, medical assessments, and drug abuse history in medical records. Descriptive statistics using t-test, chi-square test were used. Results: We found that the rate of positive urine morphine analyses was decreased gradually by the continuing intervention of the MMT. Significant differences in dosage, positive urine analyses, attendance rates between the dropout and remaining group in treatment. But no significant differences were found in age, marital status and HIV sero-status between those two groups. Conclusion: Our study findings suggest that we need to identify patients who are apt to dropout during the early stage of the MMT, and offer support and counseling. We recommend that further research need to consider an applicable intervention for this population.

並列關鍵字

methadone maintenance treatment MMT ； heroin users ； heroin dependence

參考文獻

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