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Outpatient Management of the Patients with Ovarian Hyperstimulation Syndrome

以門診方式治療卵巢過度刺激症候群

摘要


目的:評估以門診方式,進行經陰道腹水抽吸術治療罹患卵巢過度刺激症候群婦女之效果。 材料和方法:於1996年1月至2000年12月總共有555位婦女在本婦產科進行體外受精-胚胎移植(試管嬰兒)的治療。其中28位婦女(5.1 %)發生卵巢過度刺激症候群,包括有吸呼急促、噁心、嘔吐、腹痛、腹部膨脹合併腹水等症狀,我們在門診,不需麻醉,施行經陰道腹水抽吸術治療這些病人,使這些症狀獲得有效緩解。 結果:28位婦女,在取卵手術後,平均8.4±4.5天,即進行經陰道腹水抽吸術引流出腹水量1197±937mL,以舒緩因卵巢過度刺激症候群引起之上述不適症狀。有9位婦女需進行第2次抽吸術,有3位婦女在第1次抽吸術後10天,需要再進行第3次的抽吸術。所有28位婦女均不需要住院治療,也無特殊併發症發生。 結論:在門診進行經陰道腹水抽吸術,既簡易又安全,讓病人不需要住院,且可以有效改善卵巢過度刺激症候群的症狀。

並列摘要


Objective: To evaluate the efficacy of active management, including transvaginal paracentesis, on outpatient women at risk of ovarian hyperstimulation syndrome (OHSS). Material(s) and Method(s): From January 1996 to December 2000, a total of 555 women underwent in vitro fertilization-embryo transfer (IVF- ET) at our clinic on an outpatient basis. Of these, 28 women (5.1%) developed OHSS. These patients complained of dyspnea, nausea, vomiting, and abdominal distension with pain. Ascites was present in all 28 cases. We performed transvaginal paracentesis to relieve the symptoms of OHSS. The paracentesis were performed on an outpatient basis without anesthesia or analgesia. Result(s): The initial transvaginal paracentesis was performed at 8.4±4.5 days after oocyte retrieval, yielding an average of 1197±937 mL of ascitic fluid. Nine patients required a second paracentesis and 3 patients required a third paracetesis over the next 10 days. No complications related to the procedures were observed and, therefore, no patient was hospitalized. Conclusion(s): Outpatient transvaginal paracentesis is a simple, safe and effective treatment in relieving the symptoms of OHSS.

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