- 期刊
Infrared Spectroscopic Analysis of Urinary Tract Stones
紅外線光譜的尿路結石分析
摘要
背景 尿路結石是泌尿系統常見的疾病之一，但在中台灣結石成份分析的報告並不多。紅外線光譜儀是分析尿路結石成份的簡便儀器，本研究以此儀器分析本院病患的尿路結石。方法 從1993年8月15日至1999年12月31日，共施行了1427個尿路結石分析，結石分佈以輸尿管佔最多為77.7%，而腎結石佔16.8%，膀胱結石則佔了5.5%。大部份結石的標本是從碎石手術得來（佔89.8%），取得之結石碎片予以進行標準的紅外線譜儀檢查。結果 草酸鈣類相關結石最多佔了79.2%，感染結石佔14%，尿酸相關結石佔4.3%，而胱氨酸只佔了0.4%。從感染結石病人的尿液培養中發現變形桿菌是最多的細菌。男性病患的膀胱結石主要合併的疾病是良性前列腺增生症（80%），而女性病患則無明顯相關疾病，60%的感染結石發生在女性病患。結論 紅外線光譜儀可以檢驗很多不同來源的尿路結石碎片，草酸鈣結石是最主要的尿路結石成份。感染結石較常發生於女性病患，膀胱結石常見於前列腺增生症的病人。結石病人的進一步研究應著眼於草酸鈣結石病人，因為此類結石最多，有尿路結石的婦女應小心檢查其患尿路感染的高可能性。
關鍵字
紅外線光譜儀；結石分析；尿路結石並列摘要
Backfround. Urinary tract stones are common urological disorders. However, there have been few studies of the stone composition in Central Taiwan. Infrared spectroscopy is a simple procedure used to analyze stones. We conduced this study to evaluate the composition of urinary tract stones using infrared spectroscopy. Methods. Most of the samples (89.8%) were obtained during endourological procedures and extracorporeal shock wave lithotripsies. The stone fragments were analyzed using a standard infrared procedure. The most common spectra were in the 4000-600cm-1 region and a number of bands were identified. Results. There were 1427 stone analyses done from August 15, 1993 through December 31, 1999 in this hospital. Of the patients who had stones removed, 16.8% had kidney stones, 5.5% had bladder stones, and 77.7% had ureteral stones. The results showed that 79.2% of stones were calcium oxalate related, 14% were infectious stones, 43% were uric acid related and 0.4% were cystine. The most frequently found microorganism in urine culture for infectious stones was Proteus mirabilis. Benign prostatic hyperplasia was the major disease associated with urinary bladder stones in men (80%). However, no associated disorders were found in female patients. Foreign bodies within stones were seen in two female patients and one of them was intrauterine device. Infectious stones were predominant in female patients which consisted 60% (120/200) of the stones. Conclusions. A total of 79.2% stones were composed calcium oxalate. Infectious stones were predominantly found in female patients. Urinary bladder stones were frequently seen in older male patients with benign prostatic hyperplasia. Further study of patients with stones should focus on the calcium oxalate because it is the major composition. Women with urinary stones should be carefully examined due to the high possibility of urinary tract infection.