99mTc-ECD Brain SPECT for the Evaluation of Persistent Complaints After Mild Closed Head Injury

以鎝-99m-ECD腦部單光子射出斷層掃描評估輕微頭部創傷後病人持續的不適

莊豐如(Feng-Ju Chuang) ； 孫盛生(Shung-Shung Sun) ； 李文源(Wen-Yuan Lee)

《Mid-Taiwan Journal of Medicine》 7卷2期 (2002/06) Pp. 87-93

https://doi.org/10.6558/MTJM.2002.7(2).4

摘要

背景 本篇研究的目的在於使用鎝-99m-ECD腦部單光子射出斷層掃描來評估在輕微頭部創傷之後持續有不適存在但電腦斷層掃描結果卻無異常的病人。
方法 81位有頭部創傷病史的病人（44位男性和37位女性，年齡從21歲到76歲）來做鎝-99m-ECD腦部單光子射出斷層掃描。臨床上主要的不過包括了頭痛、記憶力變差、失眠、頭暈及眩暈。所有病人的電腦斷層掃描都沒有異常且都沒有腦血管疾病、精神障礙或藥物／酒精濫用病史。
結果 有57位病人，鎝-99m-ECD腦部單光子射出斷層掃描的結果顯示有血流異常的情形而其他24位病人則正常。
結論 鎝-99m-ECD腦部單光子射出斷層掃描對於評估輕微頭部創傷後持續有不適症狀且其形態學上完整的病人是一個很有用的評估工具。

關鍵字

輕微頭部創傷；鎝-99m-ECD腦部單光子射出斷層掃描

並列摘要

Background. We evaluated the usefulness of 99mTc-ethyl cysteinate dimer (ECD) brain single photon emission computed tomography (SPECT) for detecting brain perfusion abnormalities in patients with persistent clinical complaints and normal computed tomography (CT) findings after mild closed head injury.
Methods. We studied 81 patients (44 men and 37 women; age range: 21 to 76 yr) with a history of traumatic head injury (from 2 weeks to5years) using 99mTc-ECD brain SPECT. The major clinical complaints were headache, poor memory, insomnia, dizziness and vertigo. Brain CT scan was normal in all patients. None of the patients had previous CVA, psychiatric disorders or history of drug or alcohol abuse.
Results. Brain perfusion abnormalities were detected in57 patients on 99m Tc-ECD brain SPECT. Twenty-four patients had normal 99mTc-ECD brain SPECT.
Conclusions. 99mTc-ECD brain SPECT appears to be a very useful complement to CT for evaluating cerebral perfusion abnormalities in morphologically intact brain regions of patients with persistent neuropsychiatric complaints after mild closed head injury.

並列關鍵字

mild closed head injury；99mTc-ECD brain SPECT