- 期刊
深頸部感染發生重大併發症之探討
Deep Neck Infection With Major Complications
摘要
Objective. In an era of antibiotics, life-threatening complications may still occur in deep neck infection. Delayed identification and inadequate treatment of these serious complications are the primary causes of high morbidity and mortality. This study was undertaken to define the issues of major complications of deep neck infections. The prognosis and risk factors of such major complications are also discussed. Methods. A retrospective analysis of 20 patients with life-threatening deep neck infections treated in a single institute between 1996 and 1999 was performed. Results. The most common major complication of deep neck infection was upper airway compromise (15/20), followed by descending mediastinitis (6/20). Statistically significant factors of life-threatening deep neck infection were diabetes, Klebsiella pneumoniae infection, and extensive neck infection. Other factors with positive correlation but no statistical significance (p＞ 0.05)were odontogenic or upper airway infection, mixed flora infection, and deep neck infection involving the submandibualr space. Conclusions. Early recognition of the major complications and proper treatment may reduce the mortality of deep neck infection. Empiric antibiotics therapy should include antibiotics covering K. pneumoniae in diabetic patients.
並列摘要
Objective. In an era of antibiotics, life-threatening complications may still occur in deep neck infection. Delayed identification and inadequate treatment of these serious complications are the primary causes of high morbidity and mortality. This study was undertaken to define the issues of major complications of deep neck infections. The prognosis and risk factors of such major complications are also discussed. Methods. A retrospective analysis of 20 patients with life-threatening deep neck infections treated in a single institute between 1996 and 1999 was performed. Results. The most common major complication of deep neck infection was upper airway compromise (15/20), followed by descending mediastinitis (6/20). Statistically significant factors of life-threatening deep neck infection were diabetes, Klebsiella pneumoniae infection, and extensive neck infection. Other factors with positive correlation but no statistical significance (p＞ 0.05)were odontogenic or upper airway infection, mixed flora infection, and deep neck infection involving the submandibualr space. Conclusions. Early recognition of the major complications and proper treatment may reduce the mortality of deep neck infection. Empiric antibiotics therapy should include antibiotics covering K. pneumoniae in diabetic patients.