Acupuncture to Alleviate Radiotherapy-Induced Xerostomia: A Preliminary Report

以針灸緩解因放射治療產生口乾之初步報告

梁基安(Ji-An Liang) ； 張永賢(Yung-Hsien Chang) ； 楊世能(Shih-Neng Yang)

《Mid-Taiwan Journal of Medicine》 8卷Commemorative期 (2003/12) Pp. 268-273

https://doi.org/10.6558/MTJM.2003.8(C).2

摘要

目的 放射治療後所導致之唾液腺機能受損會造成生活品質的降低。本研究之目的在評估對於傳統方式放射治療後引起之口乾，以針灸方式加以改善。
方法 十六位患者接受針灸來改善口乾，我們利用設計問卷來評估主觀症狀的改善，其中後面八位患者並接受唾液腺造影加以測量。
結果 與正常群體相比，唾液腺接受高劑量放射者的功能有明顯受損，經由調查表發現可經由針灸得到輕至中度的改善。然而自唾液腺造影評估無法得到有意義之差別。
結論 針灸可能對口乾症狀加以緩解，然而其效果預計對仍保有部分唾液腺功能者會較顯著。

關鍵字

針灸 ； 放射治療 ； 唾液腺造影 ； 口乾

並列摘要

Objectives. Post irradiation salivary dysfunction leads to subjective distress and a pronounced decrease in quality of life. We evaluated the results of acupuncture applied to patients who suffered from xerostomia after conventional radiotherapy.
Methods. From August 2001 to July 2002, sixteen patients were enrolled to receive acupuncture to alleviate xerostomia. A questionnaire was administrated to measure the subjective response. After November 2001, eight patients agreed to receive sialoscintigraphy for an objective measure of efficacy. Their findings are compared with those from healthy control group (36 healthy subjects including 23 men, 13 women, age, 56.2+/-13.3 years).
Results. There was a significant decrement of impairment of salivary function for patients who received high dose radiation therapy. According to the questionnaire, mild to moderate relief from xerostomia was experienced. However, no statistically significant benefit of scintigraphic assessment was observed.
Conclusions. Acupuncture may contribute to the palliation of xerostomia symptoms. However, the beneficial effect is expected to be larger for those who have some remaining salivary function.

並列關鍵字

acupuncture ； radiation therapy ； sialoscintigraphy ； xerostomia