A 52-year-old female underwent transperitoneal laparoscopic bilateral nephroureterectomy with bladder cuff excision to treat transitional cell carcinoma of renal pelvis. Chronic renal insufficiency was noted before the operation. She did not have other systemic diseases or risk factors of acute pancreatitis such as biliary stone or alcoholism. Abdominal fullness with high levels of pancreatic enzymes (amylase: 687 U/L; lipase: 1342 U/L) were noted postoperatively. There were no symptoms of epigastragia or radiating back pain. The drainage fluid was clear and abdominal computed tomography did not reveal evidence of intestinal or pancreatic injuries. The clinical course was not compatible with typical acute pancreatitis. She received partial parenteral nutrition and started oral feeding 15 days after the operation. The patient no longer complained of having abdominal discomfort but high levels of pancreatic enzymes (amylase: 346 U/L, lipase: 423 U/L) were still noted five months after the operation.