Based on the nineteenth century Russian-British rivalry, Mackinder, a geopolitical strategist, developed the "Pivot Area" theory to describe the geopolitical balance between sea powers and land powers, in 1904, which he modified as "Heartland Theory". In 1943, Mackinder reviewed the changes of the international system and modified his theory again, substituting the balance-of-power of the global system among five regions for "Heartland Theory". The collapse of the Soviet Union and the rise of China reveal the possibility revising Mackinder's 1943 theory. International politics has completely changed since the collapse of the Soviet Union and with the rise of China, which has influenced the balance of power in the globe system tremendously, especially the geopolitical significance of Central Asia in Eurasia. This article follows Mackinder's theoretical context and discusses the geopolitical significance of Central Asia in Eurasia and the possibility of revising Mackinder's theory.