單次與長期阻力運動對血管內皮細胞功能之影響

Effects of a Single and Long-Term Resistance Exercise on Vascular Endothelial Function

蕭博允(Po-Yun Hsiao) ； 劉宏文(Hung-Wen Liu)

《大專體育》 159期 (2021/12) Pp. 55-63

https://doi.org/10.6162/SRR.202112_(159).0004

摘要

隨著臺灣心血管疾病盛行率有年輕化的趨勢，除了飲食控制外，規律運動也成為預防心血管疾病重要的手段。血管內皮為單層扁平細胞附著於血管內壁上，其功能透過分泌激素調節體內血流。先前研究發現動脈血管內皮細胞功能異常為罹患心血管疾病的重要風險因子，規律有氧運動可以提升血管內皮細胞功能，預防以及降低患病之機率，然而現階段阻力運動對於血管的影響尚未有一致結果。本文蒐集相關文獻，目的是探討單次與長期阻力運動對血管內皮細胞功能產生之影響以及可能之機轉，歸納出適合改善內皮細胞功能之阻力運動。統整相關研究所得結果顯示：單次阻力運動可能因運動強度高低、血壓升高與血流再分配等因素，多數文獻皆觀察到對血管內皮細胞功能有負面影響，長期阻力訓練則可以透過對運動的適應，提升內皮細胞功能及重塑血管構造，達到改善血管功能的效果。本文結語：因此，長期阻力訓練仍可視個別需求將其納入訓練課表中。

關鍵字

心血管疾病 ； 規律運動 ； 阻力訓練

並列摘要

As the incidence of cardiovascular events among the younger population of Taiwan has been increasing, regular exercise has become an important method of preventing cardiovascular disease (CVD) in addition to diet control. The vascular endothelium, a monolayer of endothelial cells located on the inner side of the vascular wall, plays a crucial role in regulating vascular blood flow. Previous articles showed that endothelial dysfunction could be a major indicator of CVD. Recent studies confirmed that regular aerobic exercise could improve endothelial function and lower the risk of CVD. However, research regarding the effects of resistance exercise on endothelial function has been inconclusive. Therefore, to determine a suitable resistance exercise program, we investigated the potential mechanism of resistance exercise effect contributing to the improvement of endothelial function. After analyzing the data, most articles show that a single resistance exercise seems to negatively affect the endothelial function, mainly due to exercise intensity, elevated blood pressure and blood redistribution. However, most research also indicates that long-term resistance training could possibly restore endothelial function via vascular structure adaptation and augmenting cell function. In conclusion, long-term resistance training is beneficial to endothelial function, and its practice should still be recommended depending on individual needs.

並列關鍵字

cardiovascular disease ； regular exercise ； resistance training

參考文獻

Beck, D. T., Casey, D. P., Martin, J. S., Emerson, B. D., & Braith, R. W. (2013). Exercise training improves endothelial function in young prehypertensives. Experimental Biology and Medicine, 238(4), 433-441. doi:10.1177/1535370213477600

Boeno, F. P., Farinha, J. B., Ramis, T. R., Macedo, R. C. O., Rodrigues-Krause, J., do Nascimento Queiroz, J., ... Reischak-Oliveira, A. (2019). Effects of a single session of high- and moderate-intensity resistance exercise on endothelial function of middle-aged sedentary men. Frontiers in Physiology, 10, 777. doi: 10.3389/fphys.2019.00777

Brownlee, M. (2001). Biochemistry and molecular cell biology of diabetic complications. Nature, 414(6865), 813-820. doi:10.1038/414813a

Buchanan, C. E., Kadlec, A. O., Hoch, A. Z., Gutterman, D. D., & Durand, M. J. (2017). Hypertension during weight lifting reduces flow-mediated dilation in nonathletes. Medicine & Science in Sports & Exercise, 49(4), 669-675. doi:10.1249/MSS.0000000000001150

Cao, L., Li, X., Yan, P., Wang, X., Li, M., Li, R., ... Yang, K. (2019). The effectiveness of aerobic exercise for hypertensive population: A systematic review and meta-analysis. The Journal of Clinical Hypertension, 21(7), 868-876. doi:10.1111/jch.13583