This paper describes a nursing experience for a pediatric patient who was infected with enterovirus. The nursing period was from September 20 to September 25, 2010. The author collected data through clinical observation and interview. With Gordon's 10 Health Functional Assessment tool, three major nursing problems were identified: sore throat loss of appetite secondary to injured oral mucosa, hyperthermia, and the primary caregiver's role tension because of the patient's unexpected medical status. Through listening and companionship, the author built up a trusting and therapeutic relationship with the family; thereafter, this reduced the family's anxiety, provided the child with appropriate care, and minimized the patient's suffering resulting from the infection. The patient was finally discharged to home. The author hopes that this experience can not only promote the author's professional skills, but also be used as a reference for other clinical nurses caring for similar cases in the future.