Managed care has evolved over the past 10 to 20 years due to the dramatically rising cost of health care. Hence, the health care delivery system of the 21st century has put emphasis on managed care and incorporated it into case management. Case management is a system of delivering patient care that focuses on improving the quality of service, utilizing resources and controlling health costs. Thus, the role of case managers has become a key position to successfully implement case management. Nurses make excellent case managers in a disease management program by virtue of their rich clinical skills, knowledge and their regular I nteractions with patients and other health care providers. Case management is a new nursing practice in Taiwan, and currently lacks preparation and standardization for practicing competencies; however, we look forward to the development and incorporation of the profession of case managers into advanced nursing practice as well as the recognition of the importance of such a role within the health care system.