Reservoir heterogeneity is the most important reason for low recovery and early excess water production. Experimental study on uniform mobility displacement was conducted to improve conformance and reduce water channeling for heterogeneous reservoir. The principle and mechanism were founded using a heterogeneous stratified reservoir model. For this model, injection slugs matching different permeable layers can flow simultaneously and achieve a piston-like flow. Mobility contour was proposed to screen polymer concentration. Displacement experiments were conducted in heterogeneous cores to estimate the EOR effect. The results show that uniform mobility displacement can improve oil recovery greater than polymer flooding and ASP flooding. This may provide a new EOR method to reduce water production for heterogeneous reservoir.