本篇報告我們提出了兩位因腦霧現象就醫接受重複性穿顱磁刺激(Repetitive transcranial magnetic stimulation, r-TMS)治療之案例,在2-4周間,根據FDA(Food and Drug Administration)protocol,治療處方:10HZ,3000 pulses/session,刺激強度:以患者測得之MT(motor threshold)值的70%開始,位置:F3-Left dorsal lateral posterior frontal cortex,on/off time: 4-second stimulation train,26-second inter-train interval,每次治療時間約為30-40分鐘,治療後產生顯著臨床改善效果,以蒙特利爾認知評估(Montreal Cognitive Assessment, MoCA),分數提升均大於3分以上,腦霧現象大幅改善,期許未來r-TMS應用於醫學上,能有效治療新冠肺炎產生之認知功能障礙。
In this study, we described two cases of patients with brain fog receiving repetitive transcranial magnetic stimulation (r-TMS) treatment. According to the FDA (Food and Drug Administration) protocol, within two to four weeks, the prescriptions were ten-HZ 3000pulses/session, with stimulation intensity starting at 70% of the measured MT (motor threshold) value of the patient; location: F3-Left dorsal lateral posterior frontal cortex; on/off time: four-second stimulation train, 26-second inter-train interval. Each treatment period is about 30-40 minutes. This treatment yields an effect of significant clinical improvement after therapy. According to Montreal Cognitive Assessment (MoCA), the score increased by more than three points in both cases, and the brain fog phenomenon was greatly improved. It is expected that the application of r-TMS in medicine in the future can effectively treat the cognitive dysfunction caused by COVID-19.