Early identification and intervention of neuromotor dysfunction of high-risk infants at neonatal intensive care unit is increasingly emphasized. Physical therapists play an important role in early assessment and intervention for high-risk infants. This review article is aimed for three purposes: (1) to introduce the theoretical concepts and testing procedure of general movement assessment: (2) to compare the predictive ability of general movement assessment and other assessments: and (3) to delineate the advantages and limits of general movement assessment. The reviewed information will help physical therapists understand general movements and provide the basis for designation of early intervention program.