Safety culture is increasingly recognized as an important strategy to improving the widespread deficits in patient safety. Accumulating studies have demonstrated the association between organizational safety culture and the occurrence of adverse events in health care organizations, especially for those providing intensive services. As a result, safety culture has been considered an alternative safety performance indicator. The Joint Commission for Accreditation of Healthcare Organizations in the United States as well as the World Health Organization include an annual assessment of safety culture in its 2007 patient safety goals. A range of different instruments are used for measuring organizational safety culture in the world and Chinese versions are available for some of them. Several large-scale safety attitude surveys are processing as a reference of the patient safety policy in Taiwan.