現今醫學已可治癒很多疾病,唯嚴重敗血症與敗血性休克之死亡率仍居高不下。更進一步說,若器官功能在敗血症治療過程中沒有受到保護,無法恢復正常功能,就算能倖存下來,可能需要依賴呼吸器、洗腎、肝功能異常、認知障礙或意識變差,這樣的生活品質未嘗不是一種折磨。因此很多有志之士組成國際研討會,透過實證醫學訂出現行治療敗血症之臨床準則。敗血症治療的關鍵在於爭取時間,如何在緊迫的時間內確實執行繁瑣的治療,執行核對清單有其重要性。執行核對清單可以幫助我們整理思緒,依輕重緩急按部就班完成治療,在第一小時內先做好重要的事,一到六小時緊接著完成次要的事,再依序完成後續治療。唯有完整的治療,才能避免敗血症引起之多重器官衰竭,幫病患爭取良好生活品質下的最大存活機會。
Many diseases can be cured with modern therapy. However, the mortality of severe sepsis and septic shock remains high. It needs to be concerned about poor life quality, if the patient survived with multiple organ dysfunctions as follows: ventilator dependent, hemodialysis, liver dysfunction, cognitive dysfunction, and consciousness disturbance. A group of international experts in management of sepsis published the guidelines to improve outcomes in severe sepsis and septic shock (2004 initial, 2008 update). The key of surviving sepsis is the speed and appropriateness of management. The checklist of clinical practice guidelines can help us follow the suggestions and do the important things step by step in time. Only exquisite treatment of sepsis can prevent sepsis-related multiple organ failure and save the patient's lives with good quality.