Spinal epidural abscess (SEA) is a rare disease with poor prognosis if not diagnosed and treated early. It typically occurs at the presence of predisposing conditions including diabetes mellitus, intravenous drug abuse, immunosuppressive therapy, cancer, renal failure and HIV infection. Back pain, fever and neurological deficit are usually considered the classical triads of symptoms. Contrast-enhanced magnetic resonance image is currently the gold standard for the diagnosis of SEA. A combination of surgical drainage of abscess and prolonged antimicrobial therapy has been considered as the treatment of choice. We reported a 58-year-old woman who admitted due to neck pain then upper limb numbness and weakness. Cervical magnetic resonance imaging revealed a cervical epidural abscess. Treatment including surgical drainage and evacuation of spinal abscess and intravenous antibiotics ameliorated the neurological deficits.