目的:探討台灣1999-2008年酒精意外中毒死亡及住院特性與趨勢,並分析住院死亡影響因子。方法:本研究以官方提供的死亡及住院次級資料,分析酒精意外中毒的原因,並計算10年期間「性別」、「年齡別」與「類別」的死亡率與住院率趨勢。結果:總計有369人酒精意外中毒死亡(死亡率0.144/10^5);1,361人住院(住院率0.548/10^5),其中,男性死亡率及住院率分別為女性的6.2倍及4.7倍,25-64歲死亡率及住院率皆高於其他年齡層。整體酒精意外中毒死亡率下降40%;住院原因前三名的「含酒精飲料(E860.0)」、「乙醇及其產物(E860.1)」及「甲醇(E860.2)」住院率分別上升469%、57%及111%。影響住院死亡的因子包括甲醇中毒(OR=5.746)與接受手術處置(OR=17.938)。結論:酒精意外中毒死亡率下降,但住院率上升,高危險族群為男性、25-64歲年齡層,甲醇中毒是住院死亡的高危險因素,未來應針對高危險族群擬定防治措施。
Objective: To explore the characteristics and trends in mortality and hospitalization as a result of unintentional alcohol poisoning, and to analyze the factors associated with inpatient mortality in Taiwan.Methods: We analyzed mortality data from official publications recording the death statistics and hospitalization data from the National Health Insurance Research Database from 1999 to 2008. The data was then age-adjusted to the Year 2000 Standard Population in order to determine trends in unintentional alcohol poisoning by sex, age, and cause of alcohol abuse among inpatients.Results: There were 369 deaths and 1,361 inpatient admissions due to unintentional alcohol poisoning, and the mortality and inpatient rates were 0.144 per 100,000 and 0.548 per 100,000 respectively. The mortality and inpatient hospitalization rates as a result of unintentional alcohol poisoning were higher in males than in females, and those aged 25-64 had higher rates than other age groups. The trend for mortality due to unintentional alcohol poisoning descended by 40% over the 10-year period; however, the three leading causes of unintentional alcohol poisoning resulting in hospitalization were ”alcoholic beverages (E860.0)”, ”ethanol and its products (E860.1)”, and ”methanol (E860.2)”, and these increased by 469%, 57%, and 111% respectively. In addition, the principal factors associated with inpatient mortality were methanol poisoning (OR=5.746) and surgical treatment (OR=17.938).Conclusions: The trend for mortality due to unintentional alcohol poisoning descended, but the rate of hospitalizations increased. The high-risk groups were males and those aged 25-64, and the highest risk for inpatient mortality was methanol poisoning. We should develop preventive programs for those in high-risk groups.