Eczema Herpeticum in Children with Atopic Dermatitis

兒童異位性皮膚炎之疱疹性濕疹

賴永清(Yung-Ching Lai) ； 徐世達(Shyh-Dar Shyur) ； 傅仁良(Jen-Liang Fu)

《Acta Paediatrica Taiwanica》 40卷5期 (1999/10) Pp. 325-329

https://doi.org/10.7097/APT.199910.0325

摘要

疱疹性濕疹，是一種致命性散播型皮膚單純型疱疹病毒感染，它通常發生在異位性皮膚炎病人或其他破壞皮膚保護層，導致無法局限單純型疱疹病毒感染等皮膚病人。
本文報告從民國七十八年至民國八十五年收集八位異位性皮膚炎兒童患者，合併有疱疹性濕疹，其中有五位男孩，三位女孩，從5個月大至6歲，平均年齡2.5歲，其實驗數據：免疫球蛋白E從39至474，平均197IU/ml，嗜酸性白血球計數從139至560，平均314/mm^3，Tzanck抹片試驗於六位病人皆陽性反應，疱疹水疱液無症狀於四位病人皆養出第一型單純型疱疹病毒，這些病人經抗病毒制劑Acyclovir治療後，皆痊癒。

關鍵字

疱疹性濕疹 ； 異位性皮膚炎 ； 單純型疱疹病毒

並列摘要

Eczema herpeticum (EH), a form of disseminated cutaneous herpes simplex virus (HSV) infection, is a potentially life-threatening disease. It usually occurs in individuals with atopic dermatitis (AD) or other preexisting dermatosis. The resulting disruption of the skin barrier decreases the ability of such individuals to localize an HSV infection. We report eight AD cases with eczema herpeticum, seen from February 1989 to January 1996.Their ages ranged from 5 months to 6 years (mean age 2.5 years), There were 5 boys and 3 girls. Their laboratory data showed: IgE: 39 to 474, mean 197 lU/ml; eosinophil count 139 to 560, mean 314/mm^3; Tzanck smear positive in 6 out of 6 patients; vesicle fluid culture positive for Herpes simplex type I in 4 out of 4 patients. All patients were treated with acyclovir and recovered.

並列關鍵字

eczema herpeticum ； atopic dermatitis ； herpes simplex virus