- 期刊
Pancreatic Tumors in Children: Report of Three Cases
小兒胰臓腫瘤：三病例報告
摘要
小兒胰臓腫瘤，是一種罕見的疾病。馬偕醫院自1981年至1996年間，曾經成功地診斷與治療了三個案例，年齡分別是十五天，四歲和十三歲，最後診斷，包括：兩例胰母細胞瘤(Pancreatoblastoma)及一例硬囊腫瘤(Solid and cystic tumor)。臨床上，它們皆以腹部硬塊，腹痛與罕有的生長遲緩，慢性下痢來表現。經過詳細的影像學（包括腹部超音波和電腦斷層攝影）與血清學，病理學檢查：前兩例甲型胎兒蛋白有明顯上昇，後一例其值正常。影像學檢查，皆可明顯見到含有低密度的囊狀腫瘤。經過外科手術治療，追蹤數年後，並未出現後遺症，癒後都非常令人滿意。故我們特別提出這樣的經驗供作參攷。
並列摘要
From 1981 to 1996, we experienced 3 cases of pancreatic tumors in children-two pancreatoblastomas (PB) and one solid and cystic tumor (SCT). The ages were 1 month, 4 years, and l3years of age respectively. The two cases of pancreatoblastoma initially presented as chronic diarrhea with failure to thrive, the other case presented with abdominal mass. All of them were studied by laboratory examination, ultrasonography, computed tomography and pathology. Increasing alpha- fetoprotein (AFP) levels were found in the 2 pancreatoblastoma cases, however, the level in the SCT case was normal. Abdominal sonography showed pancreatic masses with or without calcification, and the echogenicity may be solid and /or cystic. All patients underwent total excision of the tumors. We have reviewed the literature and find no pancreatoblastoma with chronic diarrhea was reported in young children, especially in neonate. Therefore, we suggest that young children presenting with an abdominal mass and/or weight loss should undergo imaging studies for the possibility of pancreatic tumors.
延伸閱讀
- 許惠春、李宏昌、黃富源（1990）。小兒胰臟假性囊腫的治療趨勢。當代醫學，(205)，924-927。https://doi.org/10.29941/MT.199011.0013
- Chao, H. C., Kong, M. S., Lin, S. J., Lou, C. C., & Lin, P. Y. (2000). 兒童胰臓乳頭囊狀瘤：三病例報告. Acta Paediatrica Taiwanica, 41(2), 101-105. https://doi.org/10.7097/APT.200004.0101
- 王麟玉、許玉呈、林姃慧、王金川（1994）。魏火曜兒科研究基金會教育課程－小兒胰臟假性囊腫。Acta Paediatrica Sinica，35(s_2)，51-53。https://doi.org/10.7097/APS.199411.0051
- 陳秋江（1993）。小兒胰臟疾病。當代醫學，(238)，650-655。https://doi.org/10.29941/MT.199308.0010
- Hsieh, Y. C., Huang, S. F., Chen, C. C., Lu, C. Y., Lu, M. Y., & Lin, K. H. (1999). 一孩童之非功能性胰臓內分泌瘤以腹部腫瘤表現. Acta Paediatrica Sinica, 40(3), 186-188. https://doi.org/10.7097/APS.199906.0186