Neonatal Varicella Frequently Associated with Visceral Complications: A Retrospective Analysis

新生兒期水痘常有脹氣合併症：回溯性分析

於鴻仁(Hong-Ren Yu) ； 黃懿娟(Yi-Chuan Huang) ； 楊崑德(Kuender D. Yang)

《Acta Paediatrica Taiwanica》 44卷1期 (2003/02) Pp. 25-28

https://doi.org/10.7097/APT.200302.0025

摘要

新生兒較容易受到水痘病毒感染，且往往有較高的併發症及致死率。我們分析了本院過去十五年新生兒水痘案例，幷將其分爲産前感染及産後感染兩組。産前感染組主要的併發症包括三例肝炎、兩例肺炎、一例皮膚細菌感染及一例敗血症。發燒是一個預測産前感染水痘是否發生併發症的很好指標。産後感染組都沒有這些併發症的情形。我們幷沒有致死的個案發生，這與過去的報告不同。可能是由於産後使用acyclovir治療的緣故。

關鍵字

新生兒水痘 ； 產前 ； 產後 ； 并發症 ； acyclovir

並列摘要

Neonates are very susceptible to varicella, which usually causes high mortality and morbidity rates among that age group. We analyzed the prognosis and complications of neonates with varicella in a retrospective study that assessed the clinical features, laboratory data, and clinical outcomes of twelve neonates who either had the illness or who were at risk. Based on exposure history, twelve babies were separated into prenatal and postnatal infection groups. Seven cases were categorized as having prenatal infections and five had postnatal varicella infection. Results showed that the major complications in the prenatal infection group included three cases of hepatitis, two of pneumonia, one of pyoderma and one of sepsis. The presence of fever was a good indicator for predicting complications among the prenatal infection group. These complications were not found in the postnatal infection group. We found that prenatal varicella infections appear to have a higher visceral complication rate. However, our patients had a much lower mortality rate than those reported in previous studies. This may be attributed to the administration of acyclovir after delivery.

並列關鍵字

neonatal varicella ； prenatal ； postnatal ； complication ； acyolovir