早産兒與一般足月兒在身體結構上就存在著某種程度上的差異;包括:較低的脂肪、骨髓中的礦特質、稀有元素及維生素。成長不良被認爲與其特殊營養需求有關。雖然在醫院治療期間,能提供足夠的營養。不過,昔日的研究報告已顯示,早産兒的成長發育比一般的足月兒差。所以早産兒出院後的喂食營養來源,是否需要特別教師,值得臨床醫師注意。本研究以隨機對照方式,比較出生體重1850公克以下的早産兒,喂食早産兒配方奶(n=19)與一般足月嬰兒本文奶(n=15)。發現矯正年齡一至六個月的體重、頭圍、身長兩組均無顯著差異。不過喂食早産兒配方奶者,在矯正年齡3個月有較高的BUN、磷。這些結果顯示低出生體重早産兒,出院後繼續喂食早産兒配方奶至矯正年齡六個月是可行的作法,且可能有較多的好處,例如較好的蛋白質攝取和骨質代謝。
We designed this prospective randomized controlled study to evaluate the effects of premature and standard term formula on growth, nutrient intake and biochemical response in premature infants from hospital discharge to 6 months of corrected age. Premature infants with a gestational age of ≤35 weeks and a birth weight≤1850 gm were assigned to receive premature infant formula (n=19) or a standard term infant formula (n=15). No differences were found between the two groups in weight, length, or head circumference at baseline or on follow-up. Infants fed premature formula had higher blood urea nitrogen and phosphorus at 3 months of corrected age. Those on the premature formula also had higher energy intake at 1 month of corrected age. We suggest that premature infants, especially very low birth weight infants, fed preterm infant formula after discharge until 6 months of corrected age tolerate the formula well and may benefit over those standard term formula.