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Feeding with Premature or Infant Formula in Premature Infants after Discharge: Comparison of Growth and Nutrition Status

早産兒出院後侖喂食不同配方奶的成長及營養狀況之比較

摘要


早産兒與一般足月兒在身體結構上就存在著某種程度上的差異;包括:較低的脂肪、骨髓中的礦特質、稀有元素及維生素。成長不良被認爲與其特殊營養需求有關。雖然在醫院治療期間,能提供足夠的營養。不過,昔日的研究報告已顯示,早産兒的成長發育比一般的足月兒差。所以早産兒出院後的喂食營養來源,是否需要特別教師,值得臨床醫師注意。本研究以隨機對照方式,比較出生體重1850公克以下的早産兒,喂食早産兒配方奶(n=19)與一般足月嬰兒本文奶(n=15)。發現矯正年齡一至六個月的體重、頭圍、身長兩組均無顯著差異。不過喂食早産兒配方奶者,在矯正年齡3個月有較高的BUN、磷。這些結果顯示低出生體重早産兒,出院後繼續喂食早産兒配方奶至矯正年齡六個月是可行的作法,且可能有較多的好處,例如較好的蛋白質攝取和骨質代謝。

並列摘要


We designed this prospective randomized controlled study to evaluate the effects of premature and standard term formula on growth, nutrient intake and biochemical response in premature infants from hospital discharge to 6 months of corrected age. Premature infants with a gestational age of ≤35 weeks and a birth weight≤1850 gm were assigned to receive premature infant formula (n=19) or a standard term infant formula (n=15). No differences were found between the two groups in weight, length, or head circumference at baseline or on follow-up. Infants fed premature formula had higher blood urea nitrogen and phosphorus at 3 months of corrected age. Those on the premature formula also had higher energy intake at 1 month of corrected age. We suggest that premature infants, especially very low birth weight infants, fed preterm infant formula after discharge until 6 months of corrected age tolerate the formula well and may benefit over those standard term formula.

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