Mycoplasma Pneumoniae Infection Associated with Hemolytic Anemia- Report of One Case

黴漿菌感染合併溶血性貧血

王錦莉(Jinn-Li Wang) ； 何文佑(Man-Yau Ho) ； 沈淵瑤(Ein-Yiao Shen)

《Acta Paediatrica Taiwanica》 45卷5期 (2004/10) Pp. 293-295

https://doi.org/10.7097/APT.200410.0293

摘要

免疫性溶血性貧血在兒童時期是很罕見的，冷凝集素被認爲是溶血的原因之一。然而，各種感染都可能與冷凝集素有關，黴漿菌肺炎感染是其中的一種。在兒童族群中，尤其是學齡前，黴漿菌感染常見於呼吸道疾病，但造成自體免疫溶血性貧血是很少見的。我們的病例是一個十一歲的男孩，因發燒住院，在住院當中發生嚴重的溶血(血紅素3.8 gm/dl)和血色素尿。因爲黴漿菌肺炎抗體呈陽性反應，故給予紅黴素治療，然而貧血卻未明顯改善，最後給予免疫球蛋白，才完全恢復。所以，即使是非常罕見，黴漿菌肺炎可能是自體免疫溶血性貧血的病因。

關鍵字

黴漿菌 ； 溶血性貧血 ； 免疫球蛋白

並列摘要

Immune hemolytic anemia is a rare condition in childhood. Cold agglutinins have been implicated in the etiology of the hemolysis. 1-Jowever, cold agglutinins may occur in various infections, such as mycoplasma pneumoniae and infectious mononucleosis. In children, especially of preschool age, mycoplasma pneumoniae very commonly cause respiratory tract infection, but inducing an immune hemolytic anemia is exceptional. We present here a case of cold agglutinin-related severe hemolytic anemia (Hb=3.8 gm/dl) secondary to mycoplasma pneumoniae infection who recovered completely after blood transfusion, intravenous immunoglobulin (IVIG) and medical treatment with erythromycin. It is suggested that even though very rare, mycoplasma pneumoniae may induce the occurrence of cold agglutinins and cause immune hemolytic anemia.

並列關鍵字

mycoplasma pneumoniae ； hemolytic anemia ； IVIG