Distribution of Allergens in Children with Different Atopic Disorders in Central Taiwan

中臺灣地區不同過敏疾病的兒童其過敏原之分佈

黃鴻偉(Hung-Wei Huang) ； 呂克桓(Ko-Huang Lue) ； 翁瑞宏(Ruey-Hong Wong) ； 孫海倫(Hai-Lun Sun) ； 許績男(Ji-Nan Sheu) ； 呂克修(Ko-Hsiu Lu)

《Acta Paediatrica Taiwanica》 47卷3期 (2006/06) Pp. 127-134

https://doi.org/10.7097/APT.200606.0127

並列摘要

Allergic disorders, including asthma, allergic rhinitis, and eczema, are the most common chronic childhood diseases. Exposure to house dust mites (HDMs) can exacerbate allergic disorders in sensitized individuals. The data for sensitization to HDMs and other frequent allergens amongst atopic children in Taiwan is limited. We studied 498 children (aged 2-16 years) with atopy in central Taiwan with CAP testing (Cationic Antimicrobial Protein system). Our results revealed a high prevalence of sensi ti zat ion to Dermatophagoides pteronyssinus (Der p) (90.2%), Dermatophagoides farinae (Der f) (88.2%), Dermatophagoides microceras (Der m) (79.5%), and Blomia tropicalis (Blo t) (76.7%) amongst the children. In contrast to HDM, the sensitization rates for other aeroallergens including cockroaches, dog dander, cat dander, Aspergillus fumigatus, Candida albicans, Cladosporium herbarum, Penicillium notatum were not common among the study children. With respect to age, inhaled allergen sensitization predominated in older children, whereas the inverse occurred with food allergens. In addition, a relatively higher proportion of cosensitization between Der m and the other three antigens, including Der p, Der f, Blo t was found. Our results suggest that HDMs, including Der p, Der f, Der m, and Blo t allergens, act as important inducers of symptoms in Taiwanese allergic children.

並列關鍵字

atopic disorder ； allergen ； children