Effects of Spatial Configuration of Electrodes on Patterns of Peripheral Nerve Activation and Noise Shielding

電極空間分佈對周邊神經激發與減低雜訊之影響

朱銘祥(Ming-Shaung Ju) ； 林宙晴(Chou-Ching K. Lin) ； 林昌緯(Chang-Wei Lin)

《Journal of Medical and Biological Engineering》 22卷3期 (2002/09) Pp. 153-160

摘要

在植入式功能性神經電刺激系統裡，陣列式銬型微電極是目前發展的趨勢。為了研究電極在空間中排列分佈對銬型電極在減低雜訊與電刺激激發神經選擇性的影響，以作為設計銬型電擊之考量，本研究建構二維有限元素模型模擬銬型電極長度對減低外加干擾源的影響，以及建構三維多神經束有限元素模型以模擬三種電極排列方式，分別為縱向排列、橫向排列與十字型排列，對電刺激選擇性與刺激電流之間的相關性。模擬結果顯示增加銬型電極長度有助於減低雜訊干擾，而在電刺激模擬方面，發現十字型電極排列擁有較佳的刺激區域選擇性及較小的刺激電流。

關鍵字

神經義肢 ； 微電極 ； 神經電訊號

並列摘要

Multi-electrode cuff electrodes is an important component in an implanted functional neural stimulation system. We constructed finite element models to investigate the effects of changing the spatial configuration of electrodes in a cuff electrode system on the noise shielding and activation pattern. The results could facilitate designing of cuff electrodes. For noise resistance, a 2D model with an external noise source was constructed. For activation pattern, two 3D models, a unifascicular and a multifascicular model, were constructed. Three types of electrode configurations, transverse, longitudinal and cross, on both types of 3D models were simulated. Model parameters were changed systematically and simulations were performed. For noise resistance in sensing applications, increasing the cuff length reduced the interference of external noise. For stimulation with three types of electrode arrangement, i.e., transverse, longitudinal and cross, we found cross arrangement was the best one having the advantages of both convex activated region and lower threshold current.

並列關鍵字

Neural prosthesis ； Microelectrode ； Electroneurography