Fiber-optics Based Optical Coherence Tomography for Biomedical Application

生醫應用之光纖式光學同調斷層掃描

廖坤鴻(Kun-Hung Liao) ； 羅增成(Tzeng-Cherng Luo) ； 楊志忠(Chih-Chung Yang) ； 林啟萬(Chii-Wann Lin)

《Journal of Medical and Biological Engineering》 23卷1期 (2003/03) Pp. 7-12

摘要

光學同調斷層掃描，為近年來快速進步的非侵入式醫學造影系統，其基本原理為使用低同調之光源，照射於生物組織，並以反射式干涉術量測背向散射光，可藉由不同機制之掃描方式，重建出二維或三維之生物組織影像，並具有達微米級之高空間解析度。我們完成一套光纖式光學同調斷層掃描系統，為了增加系統之臨床實用性，故以光學相位延遲器做為參考端之快速掃描，配合手持式造影探頭為樣本端之掃描，亦針對掃描深度之強度失真問題，進行最佳化補償，以增進影像之品質。

關鍵字

光學同調斷層掃描 ； 光學相位延遲器 ； 手持式造影探頭 ； 影像失真補償

並列摘要

Optical coherence tomography (OCT) is a fast evolving noninvasive imaging technology for biomedicine in recent years. Its fundamental principle is to use a low coherent light on biological sample and collect the backscattering light with an interferemeter configuration. It can achieve high spatial resolution of several micrometers and reconstruct two or three-dimensional images with various scanning mechanisms. Based on a fiber-optics based OCT, we implemented an optical delay-line on the reference arm for fast scanning speed and a handheld probe on sampling arm for surface scanning applications. We also reported a simple image compensation scheme, which is based on the distortion profile of scan depth, to enhance the image quality.

並列關鍵字

Optical coherence tomography ； Optical phase delay line ； Handheld probe ； Imaging distortion compensation