- 期刊
Tumor-induced Osteomalacia Mimics Osteoporosis: Case Report
並列摘要
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic disorder in which a neoplasm causes systemic bone demineralization. Most cases are benign, but malignant neoplasms have been reported. The prognosis is good if diagnosis is made early and treatment is adequate.We present the case of a previously healthy 40-year-old man who presented with low back pain for the previous year. The initial diagnosis was osteoporosis, but treatment with osteoporosis medications led to no significant improvement. Hypophosphatemia was found incidentally. Positron emission tomography with 18F fluoro-deoxyglucose (FDG-PET) indicated increased FDG uptake over the inner aspect of the right thigh, leading to a diagnosis of TIO. After resection of the tumor, the patient's pain completely disappeared.Differential diagnosis of bone demineralization disorders, such as osteoporosis and TIO, is important because of the different treatment strategies. Patients with TIO have good prognoses if diagnosis is made early and treatment is adequate.
延伸閱讀
- 陳永年、蔡嘉仁、陳榮福、董石城（2019）。A Retrospective Study of Association of Osteoporosis and Hypocalcemia in Patients with Cushing's Syndrome。內科學誌，30(5)，333-343。https://doi.org/10.6314/JIMT.201910_30(5).05
- Tung, M. S., Shih, C. M., Tung, M., Gupta, S., & Herrera, N. E. (1990). The Use of Bone Mineral Ratio for Early Diagnosis of Osteoporosis. Journal of Orthopaedic Surgery Taiwan, 7(1), 46-52. https://www.airitilibrary.com/Article/Detail?DocID=10116923-199003-7-1-46-52-a
- 劉夷生、陳台生、Mark Joffee、Louis M. Bell、Gershon Alpert、Stanley A. Plotkin、Mark R. Christofersen（1987）。Chronic Recurrent, Culture-Negative, Multifocal Osteomyelitis a Case Report。Acta Paediatrica Sinica，28(1)，40-43。https://www.airitilibrary.com/Article/Detail?DocID=00016578-198702-28-1-40-43-a
- Thampi, S., K.Matthay, K., Boscardin, W. J., Goldsby, R., & DuBois, S. G. (2014). Clinical Features and Outcomes Differ between Skeletal and Extraskeletal Osteosarcoma. Sarcoma, (2014), 182-189. https://doi.org/10.1155/2014/902620
- 蔡文龍（2006）。Application of plasma osteopontin concentrations in clinical diagnosis of osteoporosis〔碩士論文，中山醫學大學〕。華藝線上圖書館。https://doi.org/10.6834/CSMU.2006.00101