A wide range of postharvest pests, including rice weevils (Sitophilus oryzae), threatens wheat production in Nepal. This study was conducted to assess the efficacy of clove (Syzygium aromaticum) against rice weevils in Nepal under laboratory conditions. Seven amounts of clove (4, 2, 1, 0.5, 0.25, 0.12, and 0 g of clove bud/kg of wheat seed) were tested on three varieties of wheat (Bhrikuti, Vijaya, and NL971), and the dosage-mortality effect of clove bud was investigated. The mortality of rice weevils was indirectly correlated with the amount of clove bud added to all three varieties of wheat. The results suggest that clove buds have considerable pesticidal effects on rice weevils and can be considered as an alternative tool to control rice weevils in wheat during postharvest storage.